Balancing act: deubiquitinating enzymes in the nervous system
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چکیده
منابع مشابه
An optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes
The Ubiquitin-Proteasome Pathway (UPP), which is critical for normal function in the nervous system and is implicated in various neurological diseases, requires the small modifier protein ubiquitin to accomplish its duty of selectively degrading short-lived, abnormal or misfolded proteins. Over the past decade, a large class of proteases collectively known as deubiquitinating enzymes (DUBs) has...
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ژورنال
عنوان ژورنال: Trends in Neurosciences
سال: 2011
ISSN: 0166-2236
DOI: 10.1016/j.tins.2011.05.004